How can I optimize database queries in a Django web application to improve performance and reduce response times?

Use some of the following tips to optimize performance in a Django web application:

• Start by using Django's query optimization features like "select_related" and "prefetch_related" to minimize database hits.
• Profile and identify slow queries using Django Debug Toolbar or database logs and utilize database indexing to speed up query execution.
• Also, cache frequently accessed data with tools like Django's cache framework.
• Consider implementing pagination to limit the number of results per query, and avoid N+1 query problems by retrieving related data efficiently.
• Last but not least, remember to regularly review and optimize your database schema, and use a database monitoring tool to identify bottlenecks.