What are some effective ways to handle cross-origin requests in a Node.js application?

To handle cross-origin requests in your Node.js application, you should properly implement CORS (Cross-Origin Resource Sharing). Use the `cors` middleware in Express.js to manage your CORS settings. Configure the middleware to define which origins are allowed to access your resources, specify which HTTP methods are permitted, and set up any necessary headers. This setup acts like a gatekeeper, controlling and securing access to your resources from different origins. However, be mindful when setting your CORS policy - allowing all origins (*) can be risky and might expose your application to security vulnerabilities. So, properly configuring CORS ensures a safe and controlled way for your app to interact with different domains.